Thursday, May 31, 2012

Intellectual Ventures' Nathan Myhrvold defends patent trolling, calls tech industry immature

Intellectual Ventures' Nathan Mhyrvold

Intellectual Ventures' CEO and founder Nathan Myhrvold, who previously spent some 14 years at Microsoft Research, took the stage here at D10, and as predicted, his interview with Walt Mossberg was quite the invigorating one. You may know the man and his company for its vicious patent trolling -- or, what appears to be patent trolling. In essence, a lot of its business comes from acquiring patent portfolios, and then licensing and / or suing companies to "enforce" them. Naturally, Nathan has a radically different perspective than most sane individuals on the matter, insisting that the system isn't necessarily broken, and that "making money from enforcing patents is no more wrong than investing in preferred stock."

The talk centered predominantly around how Intellectual Ventures operates, what it does, and if its CEO feels that the "rat's nest of lawsuits" -- as Walt put it -- was getting out of control. Despite saying that his company has hundreds of people working on new inventions to help deliver medicines in Africa (in response to a question from the crowd on whether his outfit was truly helping people), he confessed that suing to enforce patents was simply another method of capitalism working. Care to take a ride on the crazy train? Head on past the break for a few choice quotes from the interview.

Continue reading Intellectual Ventures' Nathan Myhrvold defends patent trolling, calls tech industry immature

Intellectual Ventures' Nathan Myhrvold defends patent trolling, calls tech industry immature originally appeared on Engadget on Wed, 30 May 2012 14:33:00 EDT. Please see our terms for use of feeds.

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User:PizarroRickard15 - Stanford PowerToAct

Write and Speak(?) for the Ear


You and I may possibly not aspire to write wonderful books or make excellent speeches. But almost all of us want some thing to occur when we write or speak. And, the more we tailor our words for the ears of readers and listeners, the greater our chances of getting the outcomes we want.

By writing for the ear, I mean that spoken words can have a lot more power than written words. Immediately after all, when we have critical messages, we favor to deliver them verbally and personally, rather than by sending a written message.

Of course, it's not practical or achievable to deliver each message verbally. But, if we can capture some of the nuances of the spoken word we can enhance the power of our messages. When we write for the ear, our writing undergoes some subtle but important modifications. Our words, sentences, and paragraphs adjust in a number of important approaches.

Contemplate the number of pauses that happen when we speak. Most of us pause typically, much more frequently than when we write. To capture those pauses, use commas or a single of the other 'slowing' punctuation marks, such as colons and semicolons.

Writing for the ear also means shorter sentences. And even fragments of sentences. As you can envision, speech tends to greater spontaneity than written expression, which implies shorter sentences and a lot more fragments.

A lot of of the identical principles hold when we make formal speeches or presentations. Specifically if we speak from prepared notes.

Whatever we say, when we speak publicly, has to go in by way of listeners' ears. And so, if you are going to let me to belabor the apparent, we need to have to write speeches for listeners' ears, not our mouths.

You can call on a lot of quick and straightforward techniques. wordpress theme generator . For example, use short words whenever achievable. Words such as 'many' rather than 'numerous' 'use' rather than 'utilize' and 'need' rather than 'require'.

You can also speak for the ear by utilizing widespread words rather than jargon or technical words. Step back from your speech, following writing it, and ask your self if you use words that a child will realize.

We also want vivid words, words that fire up our imagination, that paint new pictures on the canvases of readers' minds. Descriptive words that convey action and emotion, words that drive tips into our heads.

Use active verbs and not passive verbs. Banish words like 'is', and 'are'. Also, check for the word 'being' and rewrite to get rid of it. Bring in verbs that do something.

Now that you have got the words you want, put them into brief sentences. A single brief sentence. Followed by one more short sentence. But, each and every as soon as in while add a longer sentence for assortment and to decrease the chances of boring your audience. And, preserve the tips simple inside these lengthy sentences.

I am biased, I know. Following spending the much better component of a decade writing and reading radio news copy, I feel it really is a good idea to write for the ear.

Try it for your self. Write something, read it out loud, and ask oneself about the impact it really is probably to have on readers. Re-write as needed, and read it aloud once more. Repeat the procedure a couple of times. By the time you finish you should have a well-crafted piece of writing, even if no 1 ever reads it aloud or hears it spoken.

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Project Management Professional Consultant - Kuwait

Project Management Professional Consultant



Job description:

Job Description::

The Consultant is expected to prepare and evaluate National Project Plans. This also includes full practical knowledge of PMBOK from PMI. Full practical experience and knowledge of Project sub-plans (e.g. Quality Management Plans, Risk Management Plans ...etc.)The consultant is also expected to review Plans and related documents and
provide a technical opinion via reports when needed.

Tasks & Responsibilities::

?????????Participate in studies and reviews of National Strategic projects.
?????????Prepare operational Plans documents for projects.
?????????Prepare, review and write the TORs and technical specifications (RfP, RfB, RfI ?etc.) to implement projects.
?????????Prepare, review and write technical reports related to Projects.
?????????Review and enhance technical requirements.
?????????Prepare evaluation criteria for projects tenders.
?????????Review and provide technical opinions in relation to contracts and yearly budgets for projects
?????????Review and prepare a payment plan for Projects on the verge of implementation.
?????????Provide department staff training and knowledge transfer.
?????????Prepare and conduct professional presentations to the Department and higher management.
?????????Prepare quarterly and yearly Departmental Projects status reports.

Skills:

Academic Requirements::

?????????Bachelor's degree in Computer Science ,or Computer Engineering, with Master's degree in Project Management ( preferable).

5- Technical skills, Capabilities and Experience:

?????????Minimum experience 15 years of planning and implementation of IT projects and Minimum 8 years in e-Government related projects.
?????????Implemented PMI's PMBOK in all projects within the last 8 years' experience period.
?????????Has full knowledge of the Project Life Cycle.
?????????Has full knowledge of PMI PMBOK Guide Fourth Edition.
?????????Has practical knowledge and experience in using PMBOK's Project
?????????Management Framework and the ability to tailor it according to the project type.
?????????Has practical knowledge and experience in using all PMP tools and techniques used in all Project Process Groups.
?????????Has practical knowledge and experience in writing all Project documents for all PMBOK's Project Management Process groups (Initiation, Planning, Execution, Monitor & Control, and Closing).
?????????Has practical knowledge and experience in using a project planning tool preferably Microsoft Project and the ability to prepare all status reports (daily/weekly/monthly) for projects.
?????????Prepare and write technical opinion reports related to all project documentation.
?????????Review, gather and write reports regarding technical requirements for the implementation and the operation of Projects.
?????????Able to write Lessons Learned reports for Projects.
?????????Review and align contractual and procurement documents according to Payment Plans and Project milestones.
?????????Review ORGANAISATION Staff training plans and write technical recommendations.
?????????Gather and write Budget requirements for projects.

Required Certification and Training::

?????????Certification PMP: Project Management Professional certificate from PMI that is not expired and has the candidate's PMP Number clearly stated in the certificate. Other certificates are not acceptable and failure in meeting this condition will give ORGANAISATION the right to reject the candidate.
?????????Certificate for use of planning tools preferably Microsoft Project.

Personal & Administrative Skills::

?????????Proactive attitude.
?????????Has the Ability to lead and direct Project Teams with team management skills.
?????????Excellent team building skills.
?????????Excellent Communication Management skills using all tools available at ORGANAISATION.
?????????Excellent Time Management skills.
?????????Excellent Problem and Risk Management skills.
?????????Excellent Conflict Management skills.
?????????Excellent Budgeting skills.
?????????Excellent English writing and speaking skills.
?????????Arabic proficiency is an asset.
?????????Excellent Decision making skills.
?????????Capable to participate in high level meetings and discussions.
?????????Able to prepare and conduct professional presentations.
?????????Excellent Public Speaking Skills.
?????????Excellent negotiation and influencing skills.
?????????Has high tolerance of stress.

Special Conditions to fulfill by the candidate for this job::

?????????Provide three references within the last 8 years in e-Government related projects only with full contact information as shown in the points below. Failure in providing any of the information and meeting this condition will give ORGANAISATION the right to reject the candidate: - Signed Reference letter from place of employment.
- Employer's full name.
- Current telephone, mobile and fax numbers.
- Email address.

Job Category: IT?[?View All IT Jobs?]
Language requirements:
Employment type: Full Time
Salary: Unspecified
Degree: Unspecified
Experience (year): 15
Job Location: Kuwait
Address: P.O. Box 66849
Dubai , UAE
Company Type Employer
Post Date: 30/05/2012 / Viewed 86 times


Apply Online

Add a comment to this job:


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Baby totes of the future are sling-stroller hybrids

14 hrs.

Toting infants and toddlers can be a hassle, especially when navigating stairs and crumbling sidewalks with the kangaroo-pouch-on-wheels known as the stroller.?

Thankfully, some parents of today and tomorrow who are taking classes between diaper changes and temper tantrums have come up with a solution: a sling-stroller hybrid that makes getting around a snap.

Together, a group of students from?MIT and the Rhode Island School of Design developed a?system that?is more sling than stroller. It looks similar to other infant carriers such as the Baby Bjorn and Ergobaby that parents wear on their chests, though with the ability to shift the precious package to one hip or the other while the free hand hoists the stroller for a jaunt up stairs or a across a busy street.

But, unlike other slings, the BuzzyBaby comes with a harness system that buckles onto the stroller to safely roll along the kiddo, giving the totee?s back and arms a rest until the next flight of stairs.

?The harness acts much like a universal remote control, providing one device to connect several,? notes The Boston Globe.?

The team came up with the idea after watching video tape of one of their members, Kin Lo, a fellow at the MIT?s Sloan School of Management, trying to navigate the stairs of a New York City subway with a stroller.?

According to market research performed by the?team, which included additional members from MIT and the Rhode Island School of Design, 77 percent of 400 mothers surveyed would find the system useful.

Apparently, this feedback is encouraging enough to turn the idea dreamed up in class into a business. The team plans to start selling their BuzzyBaby contraption in spring 2013.

--Via Atlantic Wire and The Boston Globe

John Roach is a contributing writer for msnbc.com. To learn more about him, check out his website and follow him on Twitter. For more of our Future of Technology series, watch the featured video below.

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Lenovo LePhone K800 launches, officially brings Medfield to China

Image

At CES 2012, Lenovo was the first to announce a Medfield-powered smartphone: the K800. And while it was the first to be unveiled, it couldn't beat the Lava Xolo X900 to market. Lenovo's not too worried about that, however, as the K800 has arrived in China right on schedule, having originally aimed for a Q2 launch and later refining the timeframe to the end of May. The fruits of Intel's labor can be had for the grand 'ol retail price of RMB 3,299 ($524), which gets you a 1.6GHz CPU, 1GB of RAM, Android 2.3, a 4.5-inch 720p display, an 8MP rear camera and 16GB of internal storage. We haven't heard any news of the phone reaching across the Pacific, but we're sure that won't stop the most insistent of you from grabbing a unit through alternative methods, right?

Lenovo LePhone K800 launches, officially brings Medfield to China originally appeared on Engadget on Wed, 30 May 2012 13:58:00 EDT. Please see our terms for use of feeds.

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Bloodletting Makes Comeback for Metabolic Syndrome

60-Second Health60-Second Health | Health

A small study shows that a little blood loss might improve cardiovascular health for obese people with metabolic syndrome. Katherine Harmon reports

More 60-Second Health

Showcasing more than fifty of the most provocative, original, and significant online essays from 2011, The Best Science Writing Online 2012 will change the way...

Read More??

Leeches and lances might seem like prescriptions from the past. But bloodletting might be back in vogue. A small study shows that losing a little blood might improve cardiovascular health for obese people who also have what?s called metabolic syndrome.

The study tracked 33 patients with metabolic syndrome?defined by the presence of some of an assortment of conditions, such as high cholesterol, hypertension and insulin resistance. Researchers took 300 milliliters of blood from the patients, a little less than the one pint standard donation, with a repeat treatment a month later.

After six weeks, treated adults had lower blood pressure than the control group. Glucose levels also decreased, which suggests limited blood removal might improve metabolic health. The findings are in the journal BMC Medicine. [Khosrow Houschyar et al., "Effects of phlebotomy-induced reduction of body iron stores on metabolic syndrome: results from a randomized clinical trial"]

The researchers think that the blood loss reduces iron levels. And excess iron in the blood has been tied to many metabolic syndrome ailments.

The FDA has okayed leeches for some procedures. Which could lead patients to thank their doctors for a treatment that sucks.

?Katherine Harmon

[The above text is an exact transcript of this podcast.]


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Rodgers to become Liverpool boss: report

[ [ [['Connery is an experienced stuntman', 2]], 'http://yhoo.it/KeQd0p', '[Slideshow: See photos taken on the way down]', ' ', '630', ' ', ' ', ], [ [['Connery is an experienced stuntman', 7]], ' http://yhoo.it/KpUoHO', '[Slideshow: Death-defying daredevils]', ' ', '630', ' ', ' ', ], [ [['know that we have confidence in', 3]], 'http://yhoo.it/LqYjAX ', '[Related: The Secret Service guide to Cartagena]', ' ', '630', ' ', ' ', ], [ [['We picked up this other dog and', 5]], 'http://yhoo.it/JUSxvi', '[Related: 8 common dog fears, how to calm them]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 5]], 'http://bit.ly/JnoJYN', '[Related: Did WH share raid details with filmmakers?]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 3]], 'http://bit.ly/KoKiqJ', '[Factbox: AQAP, al-Qaeda in Yemen]', ' ', '630', ' ', ' ', ], [ [['have my contacts on or glasses', 3]], 'http://abcn.ws/KTE5AZ', '[Related: Should the murder charge be dropped?]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 5]], 'http://yhoo.it/JD7nlD', '[Related: Bristol Palin reality show debuts June 19]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 1]], 'http://bit.ly/JRPFRO', '[Related: McCain adviser who vetted Palin weighs in on VP race]', ' ', '630', ' ', ' ', ], [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['the 28-year-old neighborhood watchman who shot and killed', 15]], 'http://news.yahoo.com/photos/white-house-stays-out-of-teen-s-killing-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120411/martinzimmermen.jpg', '630', ' ', 'AP', ], [ [['Titanic', 7]], 'http://news.yahoo.com/titanic-anniversary/', ' ', 'http://l.yimg.com/a/p/us/news/editorial/b/4e/b4e5ad9f00b5dfeeec2226d53e173569.jpeg', '550', ' ', ' ', ], [ [['He was in shock and still strapped to his seat', 6]], 'http://news.yahoo.com/photos/navy-jet-crashes-in-virginia-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120406/jet_ap.jpg', '630', ' ', 'AP', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]

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Wednesday, May 30, 2012

Prototype iPad sells for $10,200 on eBay

4 hrs.

An early prototype of the iPad with a surprising design quirk has sold for just?over $10,000 on eBay. The device features two dock connection ports, something that was rumored for the iPad 2. Unfortunately, the novelty of the two ports will be somewhat dampened by the fact that this iPad only runs a testing platform called Switchboard instead of iOS.

As the seller describes it:

This is one of a VERY small amount of Apple prototype devices and you rarely see these on ebay. This iPad has 16GBs of capacity, and is incredibly unique?...?Apple prototyped these iPads to have this connector late in the process and at the last minute decided to remove them. There are patent drawings and leaked casings that show the indents for both dock connector holes, but this unit has both dock connectors, and both are full functional for charging this iPad and connecting it to your computer.

There were certainly rumors to the effect that a new iPad would have two ports, and as the seller notes there were actually leaked cases and drawings that showed this design. This particular iPad, however, is the first actual device to show up with the ports intact.

Whether Apple indeed intended to include both ports up until "the last minute" is anyone's guess, though it seems unlikely that Steve Jobs and Jonathan Ive, both decisive and minimalistic in their design tendencies, would allow such an ambiguity into a shipping product.

It is, however, possible and even likely that the decision of which side the dock would be on was left until the last minute, as the device is equally usable in both landscape and portrait modes. They settled?on portrait as the primary orientation, clearly, mirroring the iPhone and differentiating the iPad from widescreen monitors and TVs.

Interestingly, as a commenter points out at MacRumours, which found the listing, the circuitry necessary for the second dock connector is still present in normal iPads, though there is no hole in the case through which it can be accessed.

The real question, of course, is how did this device get out of Apple's labs in the first place? The seller tells Wired: "Judging by how Apple works, it?s most likely stolen, but I?m not sure about that...?I can?t give much information about the Apple device without revealing who specifically I am." That may put this auction in questionable legal territory.

Regardless, the package is already in the open, in transit?to the US-based buyer. Apple may try to track it down, but this cat is already out of the bag.

Devin Coldewey is a contributing writer for msnbc.com. His personal website is coldewey.cc.

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Futulele goes live for iPad, ukelele serenades just went multi-touch (video)

Image

Futulele has come a long way since we saw it in March; it's now on the App Store and has put on a lot of sheen in return for slipping past the original April release target. Along with a few more flowers to reinforce the Hawaiian vibe, Amidio's definitive ukelele app has since gained the requisite support for the new iPad's graphics and a fully automatic mode, just in case you're not yet a virtual Jake Shimabukuro. If your ambitions do involve playing for yourself, you still have access to the promised maximum 132 chords (12 per set) with the flexibility to adjust chorus, delay, EQ and reverb in addition to recording those plucky creations. We're still waiting on the Futulele Remote app (and matching case) to choose chords more like we would on the real deal, but you can do it all on the iPad for now if you're willing to spend a fiver at the App Store. A flower necklace and an impressionable young lover are optional.

Continue reading Futulele goes live for iPad, ukelele serenades just went multi-touch (video)

Futulele goes live for iPad, ukelele serenades just went multi-touch (video) originally appeared on Engadget on Tue, 29 May 2012 00:21:00 EDT. Please see our terms for use of feeds.

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Foie gras feeding frenzy grows as Calif. ban nears

This is not a good time to be a duck with a fatty liver in California, though better times lie just ahead.

Chefs are loading their high-end menus with duck liver: terrine de foie gras, seared foie gras with mango chutney, foie gras salad and sweet foie gras for dessert: And they are keeping secret the locations of their multi-course dinners to avoid protesters as a July 1 ban looms in California, the only state to outlaw foie gras.

Demand for the delicacy created by force-feeding ducks through funnel-like tubes has never been higher as diners sate their palates with a product that soon will be banned for production and sale in the Golden State.

"The price has doubled. People are finding it hard to get it because the demand is so high," said Tracy Lee of the San Jose-based traveling dining service Dishcrawl, which has organized a series of 15 secret, sold-out foie gras dinners. Her last one is Thursday.

While gourmands stockpile foie gras at $60 a pound, others are stomaching the frenetic food fest with disdain.

"High-end foodies and chefs stuffing down their throats excessive amounts of fatty liver from force-fed ducks in the run-up to the ban paint a pretty ironic picture," said Jennifer Fearing of the Humane Society of the United States.

As the California foie gras feeding frenzy escalates, protesters in San Francisco and Los Angeles are staking out restaurants and even making reservations to tie up seats at dinners they know they'll never attend.

"Many people don't know what foie gras is or how it's produced and they're horrified when we tell them," said Dana Portnoy, who shot undercover video inside a foie gras operation and organizes the San Francisco-area protests. "Occasionally we'll run into antagonistic patrons, but that's usually when we're protesting at the foie gras benefit dinners."

It's why Lee doesn't publicize the restaurants where her dinners will be held until a day before the date.

"So far we haven't had any protesters, which has been nice," she said.

The California legislature gave the state's only producer, Sonoma Artisan Foie Gras, more than seven years to come up with a cruelty-free way to fatten the duck's liver when in 2004 it voted in the ban on producing and selling foie gras. Absent that, a coalition of chefs have mounted a lobbying campaign to try to overturn the law in the future, and the foie gras dinners are funding that ongoing effort.

To the oohs and aaahs of about 30 diners, Chef Josiah Slone hosted a recent seven-course foie gras feast at his Sent Sovi restaurant in Saratoga. He started with arugula with foie gras vinaigrette, moved to foie gras mousse with tartufata and English peas and seared foie gras with savory rhubarb pie. For dessert: foie, peanut butter and chocolate.

"For me, it was more of an educational dinner to talk a little about how foie gras is produced and the science behind how it's produced," Slone said. "Yes there are two sides to it, but understanding the line between science and emotion is very important for people."

There are enough "quality ingredients out there" that his California-French menu won't be lacking when it's gone, Slone said. As someone who goes to extreme measures to source quality meat and vegetables, he thinks animal welfare advocates could end more suffering if they'd focus on practices at large confined animal farming operations producing beef, chicken and pork.

"I think the issue that the animal rights people have is a lot bigger than foie gras," Slone said. "Foie gras was sort of an easy target, sort of low-hanging fruit. But in the sense of improving conditions of animal welfare, ending some of the factory farming practices that big ag is defending is a very admirable goal."

The California ban, which maintains that over-feeding ducks using a pipe stuffed down the esophagus is cruel, comes as four animal welfare groups filed a lawsuit against the U.S. Department of Agriculture last month, making another point about foie gras. They hope to secure a national prohibition by arguing that USDA is violating the Poultry Products Inspection Act by allowing "diseased birds" to enter the food chain.

Foie gras ? French for "fatty liver" ? is made from liver swollen to 10 times its normal size, which the lawsuit argues is acute hepatic lipidosis, a condition linked to obesity in animals. Ducks' livers become so engorged by the feeding process called "gavage" that the birds can't walk and have trouble breathing.

Gavage has been outlawed in a dozen countries including Israel, the Czech Republic, Denmark, Finland, Switzerland and the United Kingdom.

___

Cone reported from Fresno. Associated Press video journalist Haven Daley and photographer Marcio Sanchez reported from Saratoga, Calif.

Contact Traci Cone at http://twitter.com/TConeAP

Associated Press

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Progress of arachidonic acid biosynthesis in microorganisms

Progress of arachidonic acid biosynthesis in microorganisms [ Back to EurekAlert! ] Public release date: 29-May-2012
[ | E-mail | Share Share ]

Contact: Feng Huiyun
zlyu@ipp.ac.cn
Science in China Press

Single cell oils (SCO), produced by and extracted from some single-celled microorganisms, are featured with high levels of the major very long chain polyunsaturated fatty acids (PUFA). SCO are essential for health and potential sources of bio-diesel. There has been a long history of interest in the exploitation of microorganisms as oil and fat providers, due to the continuing diminution of arable land and climate change making animal and plant sourced oils even more limited. However, such endeavor has been progressing hardly, mostly because the efficiencies of oil synthesis by microorganisms are normally too low to be applied in industry at a reasonable price.

The article "Ion-beam-mutation breeding of an arachidonic acid biosynthesis microorganism and its industrial fermentation control" , by Z. L. Yu and Q. Huang et al., from the Hefei Institutes of Physical Science, Chinese Academy of Sciences, published in Chinese Science Bulletin (2012) 57: 883, has started to shed light on this issue. Cells of the oil-producing fungus Mortierella alpine were genetically modified by their patented technology, known as ion beam biotechnology, and screened using procedures tailored for oil yield. They obtained one strain: 50% of its biomass was fatty acids, of which 70% is arachidonic acid.

In their report "Fats and oils in human nutrition" released in 1993, the FAO and WHO suggested that diet for infants, especially preterm infants and infants with insufficient breast-feeding, should be supplemented with adequate amounts of fatty acids with composition corresponding to fatty acids contained in breast-milk. AA and docosahexaenoic acid (DHA) are particularly important for brain development but only found in breast milk naturally. Therefore it has become a long-term focus developing AA-rich oil in microorganisms.

Over two decades ago, the authors started the project by implanting energetic ions, generated by an ion source and accelerated to certain electrical potentials, into cells of Mortierella alpine, the fungus naturally synthesizing PUFA. Implanted ions resulted in genetic mutations. They firstly screened for mutant cells producing high levels of total fatty acids, presumably resulting from mutations in genes controlling palmitic acid synthesis from acetyl CoA. In the second stage, established mutant strains from the first stage were mutated again by ion implantation and strains accumulating AA, among various kinds of fatty acids, were screened for. Such two-stage protocol was repeated until a genetically stable, AA-rich strain was obtained. Its AA yield was nearly 20 times of that of the original non-mutated strain, showing prospect of industrial application. The strain was transferred to manufacturer and a production line was thereafter constructed in Wuhan, by which fermentation control study was initiated.

Fermentation control normally involves optimization of culture media and growth condition, to reach a comprehensive and balanced nutrition supply for cell metabolism. To be used as diet supplement for infants, safety is the most critical issue therefore a simple media formulation guaranteeing minimum substrate residue was desired. Researchers tested the possibility of recycling the fungi residue after oil extraction into culture media. The "waste utilization" simplified culture media from 7 ingredients to just 2, glucose and the fungi residue, therefore reduced manufacturing costs. Data from 11 batches of fermentation in 200 m3 reactor with the minimum substrates showed that, the new strain reached an average biomass of 35.8 g/L (dry fungi cells/fermentation liquid), oil and AA contents of 18.4 g/L and 8.97 g/L respectively. This result attracted attention from more researchers.

Z. Cohen and C. Ratledge commented in their compilation "Single Cell Oils" that, "Alternative microbial sources of AA are also being sought. Already it is known there is a process for AA production in China, operated by Wuhan Alking Bioengineering Co. Ltd, using a new strain of Mortierella alpine. This process appears to operate at the 50-100 ton level."

Fatty acids from most microbial sourced oils have a similar composition with plant oils. Developing microbial oils is a promising direction for both bio-diesel industry and biological economy. The work and its related technologies reported here, such as cell modification by ion beams and recycling of fungi residue as substrate, not only developed new AA resource, but also offered new thoughts and paved a novel route for future exploration of microbial oil industry. This study has been supported by the 8th, the 9th and the 10th Five-Year National Science and Technology Plans (Projects 85-722-22-01?2001BA302B-04).

###

YU ZengLiang, WANG Ji, YUAN ChengLing, et al. Ion-beam-mutation breeding of an arachidonic acid biosynthesismicroorganism and its industrial fermentation control (in Chinese). Chinese Sci Bull(Chinese Ver), 2012, 11: 883-890.



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Progress of arachidonic acid biosynthesis in microorganisms [ Back to EurekAlert! ] Public release date: 29-May-2012
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Contact: Feng Huiyun
zlyu@ipp.ac.cn
Science in China Press

Single cell oils (SCO), produced by and extracted from some single-celled microorganisms, are featured with high levels of the major very long chain polyunsaturated fatty acids (PUFA). SCO are essential for health and potential sources of bio-diesel. There has been a long history of interest in the exploitation of microorganisms as oil and fat providers, due to the continuing diminution of arable land and climate change making animal and plant sourced oils even more limited. However, such endeavor has been progressing hardly, mostly because the efficiencies of oil synthesis by microorganisms are normally too low to be applied in industry at a reasonable price.

The article "Ion-beam-mutation breeding of an arachidonic acid biosynthesis microorganism and its industrial fermentation control" , by Z. L. Yu and Q. Huang et al., from the Hefei Institutes of Physical Science, Chinese Academy of Sciences, published in Chinese Science Bulletin (2012) 57: 883, has started to shed light on this issue. Cells of the oil-producing fungus Mortierella alpine were genetically modified by their patented technology, known as ion beam biotechnology, and screened using procedures tailored for oil yield. They obtained one strain: 50% of its biomass was fatty acids, of which 70% is arachidonic acid.

In their report "Fats and oils in human nutrition" released in 1993, the FAO and WHO suggested that diet for infants, especially preterm infants and infants with insufficient breast-feeding, should be supplemented with adequate amounts of fatty acids with composition corresponding to fatty acids contained in breast-milk. AA and docosahexaenoic acid (DHA) are particularly important for brain development but only found in breast milk naturally. Therefore it has become a long-term focus developing AA-rich oil in microorganisms.

Over two decades ago, the authors started the project by implanting energetic ions, generated by an ion source and accelerated to certain electrical potentials, into cells of Mortierella alpine, the fungus naturally synthesizing PUFA. Implanted ions resulted in genetic mutations. They firstly screened for mutant cells producing high levels of total fatty acids, presumably resulting from mutations in genes controlling palmitic acid synthesis from acetyl CoA. In the second stage, established mutant strains from the first stage were mutated again by ion implantation and strains accumulating AA, among various kinds of fatty acids, were screened for. Such two-stage protocol was repeated until a genetically stable, AA-rich strain was obtained. Its AA yield was nearly 20 times of that of the original non-mutated strain, showing prospect of industrial application. The strain was transferred to manufacturer and a production line was thereafter constructed in Wuhan, by which fermentation control study was initiated.

Fermentation control normally involves optimization of culture media and growth condition, to reach a comprehensive and balanced nutrition supply for cell metabolism. To be used as diet supplement for infants, safety is the most critical issue therefore a simple media formulation guaranteeing minimum substrate residue was desired. Researchers tested the possibility of recycling the fungi residue after oil extraction into culture media. The "waste utilization" simplified culture media from 7 ingredients to just 2, glucose and the fungi residue, therefore reduced manufacturing costs. Data from 11 batches of fermentation in 200 m3 reactor with the minimum substrates showed that, the new strain reached an average biomass of 35.8 g/L (dry fungi cells/fermentation liquid), oil and AA contents of 18.4 g/L and 8.97 g/L respectively. This result attracted attention from more researchers.

Z. Cohen and C. Ratledge commented in their compilation "Single Cell Oils" that, "Alternative microbial sources of AA are also being sought. Already it is known there is a process for AA production in China, operated by Wuhan Alking Bioengineering Co. Ltd, using a new strain of Mortierella alpine. This process appears to operate at the 50-100 ton level."

Fatty acids from most microbial sourced oils have a similar composition with plant oils. Developing microbial oils is a promising direction for both bio-diesel industry and biological economy. The work and its related technologies reported here, such as cell modification by ion beams and recycling of fungi residue as substrate, not only developed new AA resource, but also offered new thoughts and paved a novel route for future exploration of microbial oil industry. This study has been supported by the 8th, the 9th and the 10th Five-Year National Science and Technology Plans (Projects 85-722-22-01?2001BA302B-04).

###

YU ZengLiang, WANG Ji, YUAN ChengLing, et al. Ion-beam-mutation breeding of an arachidonic acid biosynthesismicroorganism and its industrial fermentation control (in Chinese). Chinese Sci Bull(Chinese Ver), 2012, 11: 883-890.



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Tuesday, May 29, 2012

Mitch Feierstein: A Hundred Billion Here, a Hundred Billion There

Last week, on 21 May, the Financial Times ran a short piece which opened thus: "There has been no official announcement. No terms or conditions have been disclosed. But Greece's banking system is being propped up by an estimated ?100 billion or so of emergency liquidity provided by the country's central bank -- approved secretly by the European Central Bank (ECB) in Frankfurt." The news barely made it into the U.S. press.

But wait up. A hundred billion Euros? Lent secretly? On unknown terms and conditions? And the entire operation conducted by a bunch of unelected officials and scarcely reported in the media?

Please don't think that these things happen in Europe but could never happen in the United States. They happen here all the time and on a colossal scale. Remember that Bloomberg fought the Federal Reserve all the way to the Supreme Court in order to establish that the Fed lent over $1.2 trillion to the U.S. banking system and that those loans went ahead unbeknownst to and unauthorized by Congress. Oh, and although I say 'the U.S. banking system' what I really mean is 'any bank that puts its hand out for some cash.' So the Federal Reserve considered it appropriate to hand over some of your dollars to such not-very-American institutions as the Royal Bank of Scotland, the Belgian bank Dexia, Credit Suisse, Deutsche Bank, the Italian Unicredit, and too many others to name.

Yet nothing happens. When Bloomberg broke its story about the Fed's secret lending program, a few other news outlets picked it up, but nothing changed. The same people are in charge of the Federal Reserve. They don't think they did anything wrong. No central banker thinks that the ECB did anything wrong by handing a hundred billion euros to the collapsing banks of a failing country. It's just the way these guys do business.

Just to be clear, though, there are alternative ways to do business. You might, for example, think that we should follow the following elementary rules: the central bank should avoid printing money and generating inflationary pressures which affect us all; bankers should lend money prudently and with proper due diligence; if those loans go bad, the banks should lose their money; and, over time, those banks are either left to go out of business (if they're dumb) or encouraged to shape up and improve (if they're not.) That system even has a name. It's called capitalism. We had it in America once.

But not any more. We live in a world where moral hazard reigns supreme, where acts of gross stupidity seem to lack consequence. Where central bankers print money and no one cares. Where banks make dumb loans and get bailed out. Where politicians just want to get reelected and know that the media is going to analyze the spin down to the very last molecule and leave the substance well alone.

Take some other recent news items. Facebook's IPO saw its shares trade up to $45 before falling back to as little as $31, a fall of some 31 percent. It is alleged that Morgan Stanley, one of the banks running the stock offering, revealed data to its institutional clients that it did not share with its retail clients -- data that, in effect, called into question whether Facebook's high valuation could be justified. Morgan Stanley insists it followed every dot and comma of the relevant regulations, and perhaps it did. But retail investors have still lost a shedload of money. And Morgan Stanley and its peers have still made a huge amount in fees. If Morgan Stanley truly did follow procedures, those procedures are plainly inadequate.

Or take JP Morgan's recent $2+ billion trading loss. That arose in a bank which prides itself on its careful risk management. Which has lobbied vociferously against regulations which would prohibit the kind of activities which led to that loss. A bank which is surely 'too big too fail' -- and in my eyes, therefore, also too big to exist.

Yet nothing changes. Just ask yourself these questions. Will the Fed never again extend secret loans to dodgy banks? Will Wall Street firms never again run an IPO that destroys billions of dollars in value for retail investors? Will Wall Street so clean up its act that it never again reports billion dollar losses because of dumb-but-greedy trades?

You know the answers. Nothing changes. In Europe at the moment, a calamity is unfolding. The Spanish bank, Bankia, has had its shares suspended as it seeks to apply for yet more state aid. The Spanish government, terrified by the way the ground is moving under its feet, is beseeching the Germans to help them borrow more money, so they can pass that money on to the same unreconstructed banks that lost it all in the first place. And meantime government deficits go on adding to the ever-less-supportable mountain of debt.

The United States is not yet in that position, but the preconditions are all here. An uncontrolled deficit. An out-of-control banking system. And politicians who would rather defer any problem than tell the truth about the mess we're in.

?

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Follow Mitch Feierstein on Twitter: www.twitter.com/PlanetPonzi

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Obama Bill: Newport Beach Charges President $35,000 For Added Security Presence (VIDEO)

California has a reputation for being an "ATM" when it comes to presidential campaigns, but one city in the Golden State is tired of bearing the hidden costs of high-end political fundraisers.

Newport Beach in Orange County, Calif., has just slapped the Obama for America campaign with a bill for $35,043.04, reports Corona Del Mar Today. The figure represents the cost of extra police officers, reserve officers and overtime pay that the city contributed to the President's visit in February of this year.

The bill was City Manager Dave Kiff's idea. In a written statement to Corona Del Mar Today, Kiff said:

I think it is appropriate to treat it like a private event -- if another private event that large and which required that much police presence occurred, we would bill the event sponsor ... If the president was here on presidential business, we likely would not have billed for that.

However, Kiff emphasized in his statement that the President's visit was still an honor. "We are of course always honored when any US official, especially the President, comes to visit our community."

Newport Beach residents told CBS2/KCAL9 that they agreed with Kiff's decision to bill the President for city services rendered.

"I don?t care what the political party is ? I am not in the President?s party," said Scott Mason, who lives on the same street that the President held his fundraiser. "If you are using the public sector to support fund-raising ... you have to pay for that."

Newport Beach residents Jeffrey and Nancy Stack hosted the breakfast fundraiser for the President. Ticket prices to the event ranged from $2,500 to $35,800.

Newport Beach's revenue department sent the invoice, dated May 10, to the Obama for America office in Chicago, reports the Los Angeles Times. As of late Thursday, there's been no official response to the bill. It's due June 9.

Newport Beach is a conservative, affluent city. The median income is estimated at $107,007 (California's median income is $60,883) and registered Republicans outnumber Democrats three-to-one.

To date, President Obama has made 10 visits to the Southland since he was elected. His most recent visit in May brought him to the home of actor George Clooney, where a star-studded fundraising event raised a record $15 million for one night. Two-thirds of the figure came from small donations across the country for a contest that would fly the winners to Los Angeles for the event.

Also on HuffPost:

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I Love The Smell Of E-commerce In The Morning | Online Business ...

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Today is the day you go live with your new web site. This web site will make or break your fledgling e-commerce web site so you need to be sure you are getting what you need from your web hosting firm. The firm you choose is directly responsible for the foundation of your web site. Much like a quality foundation for our homes to be safe, the same can be said of our web site in relation to our web hosting firm of choice.

After reading and reviewing the many different web hosts mission statements and we arrive at the point of making a decision we should keep our needs and the research we have done in mind when creating the criteria for our web hosts of choice. At this point we can decide on the web hosting firm that best suits our needs and go on from there. But when launching an e-commerce web site we need to be sure that our web host can provide us with what we need to conduct business on line.

1. Server Space

The importance of maximum server space cannot be stressed enough. The more content you intend on using on your web pages, the more storage space you will need to store and manage said content. Not to mention the e-mails that will be created to safeguard your many varied customers user and contact information necessary to execute web based transactions. This server space is typically unlimited when you are dealing with a top tier web hosting firm and procuring one of their business class hosting packages for your e-commerce web site applications.

2. Bandwidth Please

An inadequate amount of bandwidth can crush your dreams of e-commerce right out of the box. Insufficient bandwidth will cause slow load times for your web site and its many different pages of inventory. These slow loading times will in many cases contribute to a rise in your competitor?s profit margins. This can be attributed directly to the loss of clientele from a slowed load time and an overall lack luster experience for your valued customers. This can be terribly detrimental to the success of your e-commerce based business ventures and ultimately undermine the overall success of your multifaceted business. Be sure the bandwidth is more than you need to avoid this unfortunate scenario all together.

3. Shopping Carts

With the thought of e-commerce in mind for your new web site then a shopping cart is most assuredly in order. This is a tool intrinsic to providing a safe and secure environment from which they can make transactions between themselves and your web site. Not to mention the added benefit of the inventory tracking tools that come with the Volusion shopping cart for instance. This is ultimately one of the most important attributes of an e-commerce site and therefore must be made available to you via your web host of choice.

4. Emails

Last but not least we come to the importance of hosting with email accounts abounding. You need to be sure the web hosting package you have in mind will offer you the limitless emails necessary to accommodate your ever growing customer base. These emails are intrinsic to helping create an easier and more enjoyable customer interface with your web sites.

Not to mention the fact that these emails can work in tandem with your shopping cart tools to help track and showcase the items specifically sought after by each of your individual clients. Helping to create the optimal web site experience for your clientele, which will in turn lend itself to the future success of your e-commerce business venture.

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Looking for EU windows SSD VPS

Junior Guru Wannabe

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Join Date: Sep 2004

Posts: 67


can anyone recommend EU based windows vps provider with SSD drives?
Preferably netherlands DC

other requierments-

1gbit connection
min 1GB ram
min 4TB bandwidth per month

cheers




Once you go bacon...well...

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Location: USA

Posts: 2,942

Quote:

can anyone recommend EU based windows vps provider with SSD drives?
Preferably netherlands DC

other requierments-

1gbit connection
min 1GB ram
min 4TB bandwidth per month

cheers

I certainly don't mean to hijack the thread, but I do feel I should mention to you that your choice for looking for Windows should be justified by what you're looking to do with the server.

Rule of thumb: Don't use Windows unless your software specifically requires it.


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yes windows is required for software im planning to use. can't run it on linux.




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Shooting victim in serious condition

Associated Press Sports

updated 10:11 a.m. ET May 27, 2012

BUENOS AIRES, Argentina (AP) -At least one person was reported in serious condition Sunday with a bullet wound following the death of a 21-year-old man in a shootout between factions of a hooligan gang.

The state-run news agency Telam said the death occurred Saturday outside the stadium where a match between Argentine first-division clubs Lanus and All Boys was about to start. Lanus won the match 1-0.

Officials identified the dead man as 21-year-old Daniel Sosa.

Violence inside and outside stadiums has intensified in Argentina with at least five people dying this year in football-related violence, according to non-profit group Let's Save Football.

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Monday, May 28, 2012

Pressures of Parenting ? Anger Management Chicago ? If you are ...

Posted on May 28, 2012. Filed under: article, Children, family, kids, Parenting | Tags: children, Family, kids, parenting |

Anthropologist Elinor Ochs and her colleagues at the University of California, Los Angeles have studied family life as far away as Samoa and the Peruvian Amazon region, but for the last decade they have focused on a society closer to home: the American middle class. Why do American children depend on their parents to do things for them that they are capable of doing for themselves? How do U.S. working parents? views of ?family time? affect their stress levels? These are just two of the questions that researchers at UCLA?s Center on Everyday Lives of Families, or CELF, are trying to answer in their work.

By studying families at home?or, as the scientists say, ?in vivo??rather than in a lab, they hope to better grasp how families with two working parents balance child care, household duties and career, and how this balance affects their health and well-being.

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The center, which also includes sociologists, psychologists and archeologists, wants to understand ?what the middle class thought, felt and what they did,? says Dr. Ochs. The researchers plan to publish two books this year on their work, and say they hope the findings may help families become closer and healthier.

Ten years ago, the UCLA team recorded video for a week of nearly every moment at home in the lives of 32 Southern California families. They have been picking apart the footage ever since, scrutinizing behavior, comments and even their refrigerators?s contents for clues.

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The families, recruited primarily through ads, owned their own homes and had two or three children, at least one of whom was between 7 and 12 years old. About a third of the families had at least one nonwhite member, and two were headed by same-sex couples. Each family was filmed by two cameras and watched all day by at least three observers.

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Among the findings: The families had very a child-centered focus, which may help explain the ?dependency dilemma? seen among American middle-class families, says Dr. Ochs. Parents intend to develop their children?s independence, yet raise them to be relatively dependent, even when the kids have the skills to act on their own, she says.

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In addition, these parents tended to have a very specific, idealized way of thinking about family time, says Tami Kremer-Sadlik, a former CELF research director who is now the director of programs for the division of social sciences at UCLA. These ideals appeared to generate guilt when work intruded on family life, and left parents feeling pressured to create perfect time together. The researchers noted that the presence of the observers may have altered some of the families? behavior.

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How kids develop moral responsibility is an area of focus for the researchers. Dr. Ochs, who began her career in far-off regions of the world studying the concept of ?baby talk,? noticed that American children seemed relatively helpless compared with those in other cultures she and colleagues had observed.

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In those cultures, young children were expected to contribute substantially to the community, says Dr. Ochs. Children in Samoa serve food to their elders, waiting patiently in front of them before they eat, as shown in one video snippet. Another video clip shows a girl around 5 years of age in Peru?s Amazon region climbing a tall tree to harvest papaya, and helping haul logs thicker than her leg to stoke a fire.

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By contrast, the U.S. videos showed Los Angeles parents focusing more on the children, using simplified talk with them, doing most of the housework and intervening quickly when the kids had trouble completing a task.

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In 22 of 30 families, children frequently ignored or resisted appeals to help, according to a study published in the journal Ethos in 2009. In the remaining eight families, the children weren?t asked to do much. In some cases, the children routinely asked the parents to do tasks, like getting them silverware. ?How am I supposed to cut my food?? Dr. Ochs recalls one girl asking her parents.

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Asking children to do a task led to much negotiation, and when parents asked, it sounded often like they were asking a favor, not making a demand, researchers said. Parents interviewed about their behavior said it was often too much trouble to ask.

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For instance, one exchange caught on video shows an 8-year-old named Ben sprawled out on a couch near the front door, lifting his white, high-top sneaker to his father, the shoe laced. ?Dad, untie my shoe,? he pleads. His father says Ben needs to say ?please.?

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?Please untie my shoe,? says the child in an identical tone as before. After his father hands the shoe back to him, Ben says, ?Please put my shoe on and tie it,? and his father obliges.

?

Ben?s next words: ?Please get my coat from the closet.? Then his father says that Ben should get it himself.

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?Isn?t that amazing?? says Dr. Ochs. ?It?s only after he escalates that the dad asks him to do something for himself.?

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It isn?t that the kids were unable to do the tasks or that their parents didn?t express a need for help, say the researchers. Rather, the studied children didn?t seem to view it as their routine responsibility to contribute, the researchers say.

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In about 75% of the families, the mothers came home first and began to ?gyrate? through the house, bouncing between the kids and their homework, groceries, dinner and laundry, according to the group?s analysis published in the Journal of Family Psychology in 2009. When the fathers came home, 86% of the time at least one child didn?t pay attention to him.

FOLLOW UP?.

Rarely has?a Blog received as delightful a batch of letters as those sent recently by Brittany Stanzel, a fourth-grade teacher at McSwain Elementary School, in Staunton, Virginia, on behalf of her students.

The 9- and 10-year-olds weighed in on whether they feel that American kids are overly dependent on their parents to do things that they are able to do for themselves. That theme?that has been observed by researchers from UCLA?s Center on Everyday Lives of Families, as reported above.

Stanzel has given permission to quote from the letters. Here are some snippets from the pens, er, computers, of the students themselves. (They have only been edited for space.)

Some say that indeed American kids are too dependent on their parents:

Cord: ?Kids are unnecessarily dependant on their parents, because kids learn not to do anything.? Some kids even bully their parents, once I actually told my parents to clean up my drink.? I feel very guilty, what I?m trying to say is kid?s need to be responsible for themselves.?

Alice: ?I always ask my dad to get me a snack when I am perfectly capable of getting my own bag of chips and a Gatorade.? Sometimes, I don?t make my bed and my mom will do it for me.? The article really made me think of the way I behave.?

Taeshon: ?My life is kind of like that.? When I can make my own peanut butter and jelly sandwich, I sometimes make my mom do it.? I think kids need to be problem solvers.?

Sarah: ?Yes, I think that American children are unnecessarily dependent. Why you may ask? Because they are lazy bums to their parents, I can be too. Our parents work, and work. I will do stuff my mom or dad ask me. But I will ask them stuff that I could have done easily. I think some American children are lazy, and can?t do anything.?

On the flip side, several of the kids disagreed and also pointed out that the results from one sample of kids shouldn?t be generalized to all children.

Sydney: ?I think that maybe it was just the people you interviewed that depended on their parents too much.? Maybe if you interviewed some other people you would come to a different conclusion.? Maybe the kid?s parents let them act like that.?

Anna Maria: ?You did find kids who did not behave; but those kids might be spoiled, or they might not have been raised the right way. If you and the anthropologists want to see good kids with good behavior, then you should observe me and my friends.?

Carter: ?Some American kids actually do what they want and they do it themselves.?? Like me, I wake up at 7:30 and I fix my lunch and breakfast.? I even walk to school. I don?t sit back and relax.? I don?t make my mom do my work.? I think kids that are independent on their own are smart.?

Stanzel writes that ?many of the students have discussed the article/issue with their parents.? Some parents believe their children are independent already.? Others have seen an improvement since we have written to you. Carter has been making his own breakfast more often and Taeshon?s parents have said that he is helping out with household tasks more than before.?

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?The kids are oblivious to their parents? perspectives,? says Dr. Ochs.

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The researchers theorize that stems from a tendency in U.S. society to adapt to and focus on the children, rather than teaching children to focus on others. And, Americans tend to encourage children to pay attention to objects more than faces, emphasizing colors and shapes, for instance, over people, says Dr. Ochs. In Samoa, children are expected to be attentive to others from a very young age, and parents stress focusing on facial expressions, says Dr. Ochs.

?

Researchers are also examining how U.S. parents view family life and work. Parents tended to describe a ?very prescribed way of being together,? says Dr. Kremer-Sadlik.

?

They commonly used terms like ?family night,? ?family movie,? or ?family breakfast,? and it was understood that the activity was meant to be child-focused time and not include others outside the family. This same vision of ?family time? wasn?t seen in Italian families, for instance, the researchers found in work published in the journal Time and Society in 2007.

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This structured and idealized way of being together appears to pressure parents to achieve these moments and also avoid another instances that might ruin it, like a child?s temper tantrum.

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?We wanted to highlight to parents that they have a lot of other opportunities for this family time,? when they can feel united, supported and connected, says Dr. Kremer-Sadlik.

?http://www.celf.ucla.edu/

http://online.wsj.com/article/SB10001424052702304450004577277482565674646.html?KEYWORDS=elinor+ochs

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